发明名称 |
METHODS OF CHARACTERIZING DRUG ACTIVITIES USING CONSENSUS PROFILES |
摘要 |
The present invention provides methods for enhanced detection of biological response profiles. In particular, the methods of this invention allow for th e detection of biological response patterns, such as gene expression patterns, in response to different drug treatments. The methods of the invention also allow the determination of a "consensus profile" which describes a particula r class or type of biological response. In certain embodiments the consensus profile may describe the biological response of a particular group or class of drugs. In other embodiments, the consensus profile may describe an "ideal" biological response such as one associated with a desired therapeutic effect . The methods of the present invention also allow for the comparison of different biological responses. Thus, the methods of the invention may be used, e.g., to identify and/or study new drugs.
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申请公布号 |
CA2356648(A1) |
申请公布日期 |
2000.07.06 |
申请号 |
CA19992356648 |
申请日期 |
1999.12.21 |
申请人 |
ROSETTA INPHARMATICS, INC. |
发明人 |
HE, YUDONG;STOUGHTON, ROLAND;FRIEND, STEPHEN H. |
分类号 |
C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/566;G06F17/30;G06F19/00;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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