| 摘要 |
<p>A system for separating biological fluids into components, comprises a set of containers (40, 42-44) for the biological fluid to be separated and the separated components, optionally an additional container (41) for additive solution, and a hollow centrifugal processing chamber (20) having an axial inlet/outlet (7) for the biological fluid. The processing chamber contains a piston (21) movable to intake a selected quantity of biological fluid and express processed biological fluid components via the outlet. Optical means (60-69) monitor the position of piston (21) to control the amount of intaken fluid and the expression of components. A distribution valve arrangement (45-48) selectively communicates the processing chamber (20) and the containers (40-44) or places them out of communication. The system is arranged to operate in a separation mode and in a non-separation transfer mode, especially for adding preservative solution to separated blood stem cells. In the separation mode, fluids are intaken into processing chamber (20), centrifuged and separated into components, and the components expressed possibly through the use of a density gradient product. In the transfer mode, the processing chamber (20) intakes and expresses fluid with the chamber stationary, the valve actuation arrangement (45-48) transferring fluid from one container (40-44) to another via the processing chamber (20), by movement of the piston (21), without centrifugation or separation, and the means (60-69) for monitoring the piston's position controls the amounts of non-separated fluids transferred.</p> |
