PROCESS FOR PREPARING OPTICALLY ACTIVE 1-AMINO-4-(HYDROXYMETHYL) CYCLOPENT-2-ENE DERIVATIVES

摘要

The invention relates to a new method for producing enantiomer-enriched 1- amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which R1 is hydrogen or a possibly substituted C1-8 alkyl rest, aryl rest or cycloalkyl rest and R2 is a possibly substituted acyl. According to said method a racemic 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivative of general formula (III), in which R1 has the meaning given above , is converted using a hydrolase and in the presence of an acylation agent.