发明名称 LIPOSOMIC NIFLUMIC ACID - NEW TRANSDERMAL ANTI-INFLAMMATORY MEDICINE
摘要 The present invention is referred to the encapsulation of the drug Niflumic acid in liposomes with the purpose to create a new transdermal non-steroidal anti-flammatory formulation. The Niflumic acid as well as its ester derivates, have been encapsulated into liposomes with different lipid formulations in order to achieve the increased effectiveness of the active compound. The liposome suspension, with or without the encapsulated drug has been formulated as a cream and a stability study of the final formulation has followed.
申请公布号 WO0038681(A1) 申请公布日期 2000.07.06
申请号 WO1999GR00048 申请日期 1999.12.22
申请人 P.N. GEROLYMATOS S.A.;DEMETZOS, KONSTANTINOS;KAMMENOU, HELEN;RALLIS, MICHALIS;PAPAIOANNOU, GEORGIOS;GEORGOPOULOS, ARISTIDIS;TSAMOURIS, GEORGIOS;HATZIANTONIOU, SOFIA;GIANNISIS, GEORGIOS;NOUNESIS, GEORGIOS;SAVVA-DIMOPOULOU, CHRISTINA 发明人 DEMETZOS, KONSTANTINOS;KAMMENOU, HELEN;RALLIS, MICHALIS;PAPAIOANNOU, GEORGIOS;GEORGOPOULOS, ARISTIDIS;TSAMOURIS, GEORGIOS;HATZIANTONIOU, SOFIA;GIANNISIS, GEORGIOS;NOUNESIS, GEORGIOS;SAVVA-DIMOPOULOU, CHRISTINA
分类号 A61K9/06;A61K9/08;A61K9/10;A61K9/127;A61K9/70;A61K31/44;A61K31/465;A61K47/16;A61K47/24;A61K47/28;A61K51/00;A61P19/02;A61P29/00;(IPC1-7):A61K31/465 主分类号 A61K9/06
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