| 发明名称 |
USE OF A MATRIX METALLOPROTEINASE INHIBITOR AND AN INTEGRIN ANTAGONIST IN THE TREATMENT OF NEOPLASIA |
| 摘要 |
The present invention provides methods to treat or prevent neoplasia disorde rs in a mammal using a combination of a matrix metalloproteinase inhibitor, an integrin antagonist and an antineoplastic agent. |
| 申请公布号 |
CA2356402(A1) |
申请公布日期 |
2000.07.06 |
| 申请号 |
CA19992356402 |
申请日期 |
1999.12.22 |
| 申请人 |
G.D. SEARLE & CO. |
发明人 |
CUNNINGHAM, JAMES J.;GATELY, STEPHEN T.;GORDON, GARY;KOKI, ALANE T.;MCKEARN, JOHN P.;MASFERRER, JAIME L. |
| 分类号 |
A61K45/00;A61K31/07;A61K31/122;A61K31/135;A61K31/136;A61K31/138;A61K31/16;A61K31/165;A61K31/166;A61K31/18;A61K31/191;A61K31/192;A61K31/197;A61K31/198;A61K31/203;A61K31/255;A61K31/28;A61K31/282;A61K31/337;A61K31/341;A61K31/351;A61K31/353;A61K31/36;A61K31/381;A61K31/402;A61K31/415;A61K31/4162;A61K31/4164;A61K31/4168;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/4196;A61K31/42;A61K31/421;A61K31/422;A61K31/425;A61K31/427;A61K31/429;A61K31/435;A61K31/4353;A61K31/437;A61K31/4375;A61K31/44;A61K31/4402;A61K31/4418;A61K31/4427;A61K31/4433;A61K31/4439;A61K31/444;A61K31/445;A61K31/4453;A61K31/45;A61K31/451;A61K31/4535;A61K31/4545;A61K31/4709;A61K31/4741;A61K31/4745;A61K31/475;A61K31/496;A61K31/501;A61K31/505;A61K31/506;A61K31/51;A61K31/519;A61K31/525;A61K31/541;A61K31/55;A61K31/5513;A61K31/566;A61K31/567;A61K31/569;A61K31/57;A61K31/575;A61K31/66;A61K31/664;A61K31/675;A61K31/704;A61K31/7048;A61K31/7068;A61K33/04;A61K33/10;A61K33/24;A61K38/00;A61K39/395;A61K41/00;A61K45/06;A61P1/00;A61P11/00;A61P13/10;A61P15/00;A61P15/14;A61P17/00;A61P35/00;A61P41/00;A61P43/00;C07D211/54;C07D211/66;C07D211/96;C07D213/74;C07D261/18;C07D309/08;C07D401/06;C07D401/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12;C07D471/04;C07K5/023;C07K5/062;C07K16/18;(IPC1-7):A61K41/00 |
主分类号 |
A61K45/00 |
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