发明名称 (A4) ;IMPROVED TREATMENT OF MIGRAINE HEADACHE;0007 (B1) ;TREATMENT OF MIGRAINE HEADACHE USING METOCLOPRAMIDE AND AN NSAID
摘要 The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the storage life of the compositions has been increased. Also disclosed are coordinated dosage forms for the sequential release of drugs. The invention encompasses methods of treating migraine using any of these dosage forms.
申请公布号 EP1014961(A1) 申请公布日期 2000.07.05
申请号 EP19970946927 申请日期 1997.11.12
申请人 POZEN, INC. 发明人 PLACHETKA, JOHN, R.;CHOWHAN, ZAKAUDDIN, T.
分类号 A61K9/30;A61K9/20;A61K9/22;A61K9/24;A61K9/46;A61K31/12;A61K31/122;A61K31/165;A61K31/166;A61K31/19;A61K31/192;A61K31/195;A61K31/196;A61K31/40;A61K31/407;A61K31/42;A61K31/421;A61K31/54;A61K31/5415;A61K45/00;A61K47/32;A61K47/38;A61K47/46;A61P25/06;(IPC1-7):A61K31/165 主分类号 A61K9/30
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