| 摘要 |
PCT No. PCT/JP97/03247 Sec. 371 Date May 6, 1999 Sec. 102(e) Date May 6, 1999 PCT Filed Sep. 12, 1997 PCT Pub. No. WO98/11118 PCT Pub. Date Mar. 19, 1998A novel fluorine-containing Lewis X derivative represented by the following formula (I): wherein R represents hydrogen, a hydroxyl-protective group, -PO(OH)2, -SO3H or sialylate; R1 represents hydrogen, hydroxyl, aliphatic acyloxy, aromatic acyloxy, lower alkylthio, optionally substituted phenylthio, lower alkoxy, branched long chain alkoxy, optionally substituted phenylmethoxy or sphingosinyl, R10 represents hydrogen or -O-C-(=NH)CCl3; provided that when R10 is -O-C-(=NH)CCl3, R9 is hydrogen; R2 and R3 are the same or different and independently represent hydrogen, aliphatic acyl, aromatic acyl or optionally substituted phenylmethyl; and R4 represents hydroxyl, aliphatic acyloxy, aromatic acyloxy, aliphatic acylamino or aromatic acylamino.
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