| 摘要 |
A compact fluidic circuit card having a main body with internal sensing elements and with fluidic circuit components (FCCs) located on both its front and back surfaces. An immunoassay sensing element may be used either in the form of a optical waveguide around which the liquid test sample may flow, or a disc through which the liquid test sample may flow. The card may be made inexpensive enough to be disposable by forming its main body and all of its FCCs so that they are suitable for being integrally formed in one piece by injection molding from plastic, regardless of the number of its FCCs; and by using thin strips of adhesively attached material for the main body's cover, needle septum strip and valve membrane strip. Heat-shrink plastic may be used for the valve membranes. The strength of the heat-shrink plastic's adhesive bonds may be increased by using a corona or plasma discharge to intentionally damage the surface of the heat-shrink plastic. Cross contamination between liquids in the card may be prevented by using separating bubbles, large radius turns in the channels, and valve cavities shaped to permit the valve membranes to empty them completely when the valve is closed. Mass transfer enhancing components may be provided to increase the rate at which the target material in the liquid test sample reaches the sensing element. Either transmissive or reflective light source and photodetector pairs may be used to detect fluids and bubbles in the card; and to read information encoded on the card.
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