| 发明名称 |
Water soluble vitamin B12 receptor modulating agents and methods related thereto |
| 摘要 |
Vitamin B12 receptor modulating agents capable of modulating cell surface receptors by affecting the cell surface receptor trafficking pathway are disclosed. The vitamin B12 receptor modulating agents are comprised of a covalently bound rerouting moiety and targeting moiety linked by a water-solublizing linker.
|
| 申请公布号 |
US6083926(A) |
申请公布日期 |
2000.07.04 |
| 申请号 |
US19980200422 |
申请日期 |
1998.11.23 |
| 申请人 |
THE UNIVERSITY OF WASHINGTON;RECEPTAGEN CORPORATION |
发明人 |
MORGAN, JR., A. CHARLES;WILBUR, D. SCOTT;PATHARE, PRADIP M. |
| 分类号 |
A61K31/70;A61K31/7135;A61K31/714;A61K38/00;A61P1/00;A61P1/16;A61P11/00;A61P13/02;A61P15/00;A61P17/00;A61P25/00;A61P35/00;A61P35/02;A61P43/00;C07H23/00;G01N33/567;(IPC1-7):A61K31/70 |
主分类号 |
A61K31/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
