发明名称 |
Sustained release formulation containing three different types of polymers and tablet formed therefrom |
摘要 |
Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent gelling polymer such as an alginate component, (2) an enteric polymer component, such as Eudragit TM L or S, and (3) a pH independent gelling polymer, such as hydroxy propyl methyl cellulose or polyethylene oxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.
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申请公布号 |
US6083532(A) |
申请公布日期 |
2000.07.04 |
申请号 |
US19970985986 |
申请日期 |
1997.12.05 |
申请人 |
DURAMED PHARMACEUTICALS, INC. |
发明人 |
ZHANG, GUOHUA;PINNAMARAJU, PRASAD;ALI, MUHAMMAD |
分类号 |
A61K9/20;A61K9/22;A61K31/275;A61K31/277;A61K47/32;A61K47/36;A61K47/38;(IPC1-7):A61K9/22 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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