| 发明名称 |
Near infrared radiation in-vivo diagnostic methods and dyes |
| 摘要 |
PCT No. PCT/DE95/01465 Sec. 371 Date Nov. 7, 1997 Sec. 102(e) Date Nov. 7, 1997 PCT Filed Oct. 10, 1995 PCT Pub. No. WO96/17628 PCT Pub. Date Jun. 13, 1996This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
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| 申请公布号 |
US6083485(A) |
申请公布日期 |
2000.07.04 |
| 申请号 |
US19970849369 |
申请日期 |
1997.11.07 |
| 申请人 |
INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH;DER FREIEN UNIVERSITAT BERLIN |
发明人 |
LICHA, KAI;RIEFKE, BJORN;SEMMLER, WOLFHARD;SPECK, ULRICH;HILGER, CHRISTOPH-STEPHAN |
| 分类号 |
C07D403/06;A61K;A61K49/00;C07D209/14;C07D209/18;C07D209/60;C09B23/00;C09B23/08;C09B69/10;(IPC1-7):A61K49/00;G01N31/00;G01N33/48 |
主分类号 |
C07D403/06 |
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