摘要 |
An apparatus for delivery of a therapeutic agent to a target tissue in vivo is provided which permits delivery of agents such as proteins, nucleic acids, liposomes, lipids, sugars, glycolipids, prodrugs, vectors, or chemotherapeutics for treating cancer, or genetic material for gene therapy directly to a target tissue in vivo, such as a tumor, or an internal organ of a subject. Hence, delivery of the therapeutic agent is independent of the circulatory system of the subject. Furthermore, since the agent is delivered directly to the target tissue, the effect of the therapeutic agent at the target tissue is maximized, and deleterious effects on collateral organs are minimized. |