发明名称 Heteroaryl-aryl ureas as igf-1 receptor antagonists
摘要 Methods for treating diseases associated with the activity of the insulin growth factor-1 receptor (IGF-1R), such as cancer, are provided. Methods for inhibiting cell growth and proliferation, especially of tumor cells, and promoting apoptosis are also provided. Each of these methods employs the use of a heteroaryl-aryl urea compound as an antagonist for IGF-1R.
申请公布号 AU2711400(A) 申请公布日期 2000.07.03
申请号 AU20000027114 申请日期 1999.12.17
申请人 TELIK, INC. 发明人 MICHAEL R KOZLOWSKI;ROBERT T LUM;STEVEN R. SCHOW;HUGO O VILLAR;MICHAEL M. WICK
分类号 A61K31/425;A61K31/47;A61K31/4706;A61P35/00 主分类号 A61K31/425
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