| 发明名称 |
Methods and compositions for treating disorders involving excitotoxicity |
| 摘要 |
It is shown here that hedgehog polypeptides possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons and other neurons which are sensitive to exotoxicity. |
| 申请公布号 |
AU2352200(A) |
申请公布日期 |
2000.07.03 |
| 申请号 |
AU20000023522 |
申请日期 |
1999.12.03 |
| 申请人 |
BIOGEN, INC.;ONTOGENY, INC. |
发明人 |
ALPHONSE GALDES;NAGESH MAHANTHAPPA |
| 分类号 |
C12N5/06;A61K38/00;A61K38/17;A61K45/00;A61P3/08;A61P25/00;A61P25/04;A61P25/10;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P31/18;A61P39/02;A61P43/00 |
主分类号 |
C12N5/06 |
| 代理机构 |
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代理人 |
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