发明名称 |
Plasma like solution and methods of use |
摘要 |
Aqueous solutions comprising a polysaccharide oncotic agent, a physiologically compatible buffer, a simple hexose sugar, dissolved chloride salts of calcium, sodium and magnesium, and a dissolved organic salt of sodium are disclosed. The solutions are effective substitutes for blood and may be used to preserve the biological integrity of the organs of a mammalian donor organism as shown by superior anatomical integrity of cryopreserved organs and tissues of subjects perfused with the solution. The solutions may be used for maintaining a partially or substantially completely exsanguinated subject at normal temperatures and at temperatures substantially below those normally maintained by a mammal and may be used in conjunction with hypobaric environments to maintain such partially or completed exsanguinated subjects alive without infusing blood back into the subject.
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申请公布号 |
US6080538(A) |
申请公布日期 |
2000.06.27 |
申请号 |
US19970896823 |
申请日期 |
1997.07.18 |
申请人 |
BIOTIME, INC. |
发明人 |
SEGALL, PAUL E.;STERNBERG, HAL;WAITZ, HAROLD D.;SEGALL, JUDITH M. |
分类号 |
A61K33/00;A01N1/02;A61K9/00;A61K31/00;A61K31/19;A61K31/718;A61K33/06;A61K33/10;A61K33/14;A61K35/14;A61P7/08;(IPC1-7):A01N1/02;A61M31/00 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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