| 摘要 |
PCT No. PCT/GB97/00404 Sec. 371 Date Aug. 13, 1998 Sec. 102(e) Date Aug. 13, 1998 PCT Filed Feb. 13, 1997 PCT Pub. No. WO97/30056 PCT Pub. Date Aug. 21, 1997The present invention is directed to spiro-ketal derivatives of the formula (I): (wherein R, R1, R2, R3, R4, R5, R6, R9a, R9b, m and n are defined herein) which are tachykinin antagonists and are useful, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
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