| 摘要 |
PURPOSE: Acetone complexes of sulfoxide compounds, a process for producing them and a purification method of using them are provided which is useful as medicines such as inhibitors of gastric acid secretion and anti-ulcer agents or as intermediates for production of medicines. CONSTITUTION: Acetone complexes of sulfoxide compounds or of pharmaceutically acceptable salts thereof are represented by the following formula(I): wherein R1 represents a hydrogen atom, a method group or a difluoromethoxy group, R2 represents a methyl group or a method group, R3 represents a 3-methodpropoxy group, a method group or a 2,2,2-trifluoroethoxy group, R4 represents a hydrogen atom or a methyl group, n and m independently represent an integer of 1 to 4, and B represents a hydrogen atom, an alkali metal atom or 1/2 alkaline earth metal atom. The formula are obtained by treating the sulfoxide compounds or pharmaceutically acceptable salts thereof with acetone.
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