AQUEOUS SOLUTION COMPOSITIONS COMPRISING POLYMER HYDROGEL COMPOSITIONS

摘要

PURPOSE: An aqueous solution compositions comprising polymer hydrogel compositions is provided which is capable of trapping water insoluble beneficial agent, yet capable of disintegrating smoothly to impart desirable in use characteristics. CONSTITUTION: An aqueous composition comprises: (a) 40-95% by weight aqueous solution having a viscosity greater than 300 centipoises; and (b) 5% to 60% by wt. of a hydrogel composition comprising: (i) 0.1 to 30% by wt. hydrogel composition of at least one polymer soluble in water which polymer is in solubilized when placed in the aqueous solution of item (a); (ii) 0.2 to 30% by wt. hydrogel composition of a polymer soluble in water, and soluble or dispersible in the aqueous solution of item (a); and (iii) 1.0 to 602 water insoluble benefit agent entrapped in a network formed by (i) and (ii): wherein the particles of the benefit agent (iii) have particle size of 0.2 to 200 micrometers; wherein the hydrogel is greater than 25 micrometers; and wherein the size of the hydrogel (b) is greater than that of the benefit agent.