| 摘要 |
Compositions containing a farnesyl transferase inhibitor (I) and a topoisomerase inhibitor (II). Compositions containing a farnesyl transferase inhibitor of formula (I) in racemic or optical isomeric form, and its salts and a topoisomerase inhibitor (II). Ar = 2,3-dihydro-1,4-benzodioxin-6-yl , 2,3-dihydrobenzofuran-5-yl or substituted phenyl; R = COOH, -COOMe or -CONH(R8); R1, R2 = H or methoxy; provided that R1 and R2 are different; R3, R4 = H and one may also be methoxy; R5 = H or methyl; R8 = methyl substituted by 3-pyridyl; X = methylene or vinyldiyl.
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