| 发明名称 |
Prodrug compounds and process for preparation thereof |
| 摘要 |
The prodrug of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the enzyme trouase. Also disclosed are processes for making the prodrug compounds. |
| 申请公布号 |
AU2373300(A) |
申请公布日期 |
2000.06.26 |
| 申请号 |
AU20000023733 |
申请日期 |
1999.12.10 |
| 申请人 |
COULTER PHARMACEUTICAL, INC. |
发明人 |
THOMAS J. LOBL;VINCENT DUBOIS;ANNE-MARIE FERNANDEZ;SANJEEV GANGWAR;EVAN LEWIS;MATTHEW H. NIEDER;ANDRE TROUET;PETER VISKI;GEOFFREY T. YARRANTON |
| 分类号 |
A61K31/138;A61K31/165;A61K31/198;A61K31/337;A61K31/407;A61K31/437;A61K31/4745;A61K31/513;A61K31/519;A61K31/52;A61K31/5517;A61K31/555;A61K31/7004;A61K31/7028;A61K31/7048;A61K31/7064;A61K31/7068;A61K33/24;A61K47/42;A61K47/48;A61P29/00;A61P35/00;C07K5/10;C07K7/00 |
主分类号 |
A61K31/138 |
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