发明名称 |
Aqueous formulations of peptides, preferably LHRH |
摘要 |
This specification describes stable liquid aqueous formulations of peptide compounds at high concentrations. These stable formulations comprise at least about 10 % peptide in water. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug. Preferred peptides include leuprolide, LHRH, nafarelin and goserelin.
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申请公布号 |
NZ333579(A) |
申请公布日期 |
2000.06.23 |
申请号 |
NZ19970333579 |
申请日期 |
1997.07.01 |
申请人 |
ALZA CORPORATION |
发明人 |
ECKENHOFF, JAMES B;STEVENSON, CYNTHIA L;TAO, SALLY A;PRESTRELSKI, STEVEN J;WRIGHT, JEREMY C;LEONARD, JOE |
分类号 |
A61K47/16;A61K9/00;A61K9/08;A61K38/00;A61K38/04;A61K38/08;A61K38/09;A61K38/22;A61K38/24;A61K38/27;A61K38/38;A61K47/02;A61K47/08;A61K47/18;A61K47/20;A61P35/00;A61P43/00;(IPC1-7):A61K47/20 |
主分类号 |
A61K47/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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