发明名称 Amino acid derivatives and their use as thrombin inhibitors
摘要 Amino acid derivatives of formula (I) are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required or as anticoagulants.
申请公布号 NZ311854(A) 申请公布日期 2000.06.23
申请号 NZ19960311854 申请日期 1996.07.02
申请人 ASTRA AKTIEBOLAG 发明人 GUSTAFSSON, DAVID;NYSTROM, JAN-ERIK
分类号 C07K5/06;A61K31/395;A61K31/397;A61K31/40;A61K31/4025;A61K31/443;A61K31/445;A61K38/05;A61K38/55;A61P7/02;C07D205/04;C07D207/16;C07D211/60;C07D405/06;(IPC1-7):A61K38/55 主分类号 C07K5/06
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