| 发明名称 |
Herpesvirus saimiri as viral vector for genetic therapy |
| 摘要 |
A herpesvirus saimiri that has been genetically modified by mutating and/or deleting specific essential and non-essential genes. The mutation of ORF50 and/or ORF57 genes prevents viral replication in a human cell. The non-essential genes can represent sites for the insertion of heterologous genetic material, namely therapeutic genes.
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| 申请公布号 |
NZ334323(A) |
申请公布日期 |
2000.06.23 |
| 申请号 |
NZ19970334323 |
申请日期 |
1997.09.04 |
| 申请人 |
THE UNIVERSITY OF LEEDS |
发明人 |
MEREDITH, DAVID MARK;MARKHAM, ALEXANDER FRED |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;C07K14/03;C12N7/00;C12N7/01;C12N15/869;(IPC1-7):C12N7/01;C12N15/89;C12N15/38 |
主分类号 |
C12N15/09 |
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