发明名称 |
ISOLATION OF HUMAN PEMT2 GENE AND METHODS FOR DIAGNOSING AND TREATING LIVER DISORDERS |
摘要 |
This invention relates to isolated nucleic acid molecules associated with liver disorders, in particular, nucleic acid molecules encoding human phosphatidylethanolamine N-methyltransferase-2 (PEMT2). This invention is further directed to methods for identifying individuals having or at risk of having PEMT-associated liver disorders. This invention also provides pharmaceutical compositions and methods for treating PEMT-associated liver disorders by modulating the phosphatidylethanolamine N-methyltransferase (PEMT) pathway and the phosphocholine cytiylyltransferase (CT) pathway.
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申请公布号 |
WO0014198(A9) |
申请公布日期 |
2000.06.22 |
申请号 |
WO1999US18463 |
申请日期 |
1999.08.13 |
申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
VANCE, DENNIS, E.;WALKEY, CHRISTOPHER, J.;CUI, ZHENG |
分类号 |
A61K38/00;A61K48/00;C12N9/10;(IPC1-7):C12N/ |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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