| 发明名称 |
4-ARYLOXINDOLES AS INHIBITORS OF JNK PROTEIN KINASES |
| 摘要 |
Novel 4-aryloxindoles having formula (I), where, R2, R3, X and A as set fort h in the specification inhibit or modulate protein kinases, in particular JNK protein kinases and are useful as anti-inflammatory agents, partiuclarly in the treatment of rheumatoid arthritis.
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| 申请公布号 |
CA2354591(A1) |
申请公布日期 |
2000.06.22 |
| 申请号 |
CA19992354591 |
申请日期 |
1999.12.09 |
| 申请人 |
F. HOFFMANN-LAROCHE AG |
发明人 |
CORBETT, WENDY LEA;MAHANEY, PAIGE E.;LUK, KIN-CHUN |
| 分类号 |
A61K9/00;A61K31/404;A61K31/4178;A61K31/506;A61P29/00;A61P43/00;C07D403/06;C07D403/14;C07D405/14;C07D409/14;(IPC1-7):C07D403/06;A61K31/40 |
主分类号 |
A61K9/00 |
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