1,2-dithiolane derivatives, their process of preparation and pharmaceutical compositions containing them

摘要

1,2-dithiolane derivatives (I) are new. 1,2-dithiolane derivatives of formula (I) and their acid or base addition salts are new. Ra = 1-8C alkylene; Rb = bond or 1-6C alkylene; Z = -O-C(S)-N(R1)- or -C(S)-N(R1)- (N being attached to Rb); R1 = H, 1-6C alkyl, aryl or 1-6C aralkyl; T = a group of formula (i); R2, R3 = H, 1-6C alkyl, cycloalkyl, heterocycloalkyl, heterocycloalkylalkyl, aryl, 1-6C aralkyl, heteroaryl, heterarylalkyl, 1-6C aminoalkyl (amino being optionally substituted with 1 or 2 1-6C alkyl, aryl or 1-6C aralkyl). Independent claims are also included for: (1) the preparation of (I); and (2) pharmaceutical compositions comprising at least one (I).