Thermophilic DNA polymerases from Thermotoga neapolitana
摘要
The present invention relates to compositions of thermostable DNA polymerases derived from the hyperthermophilic eubacteria. In particular, the present invention comprises thermostable DNA polymerases from the hyperthermophilic eubacterium known as Thermotoga neapolitana. The present invention provides methods for utilizing naturally-occurring and non-naturally-occurring forms of T. neopolitana DNA polymerase. The T. neopolitana DNA polymerases of the present invention are used in combination with other compounds, including but not limited to pyrophosphatase and DNA polymerases from other thermophilic or hyperthermophilic organisms.
申请公布号
US6077664(A)
申请公布日期
2000.06.20
申请号
US19960656664
申请日期
1996.05.31
申请人
PROMEGA CORPORATION
发明人
SLATER, MICHAEL R.;HUANG, FEN;HARTNETT, JAMES R.;BOLCHAKOVA, ELENA;STORTS, DOUGLAS R.;OTTO, PAUL;MILLER, KATHARINE M.;NOVIKOV, ALEXANDER;VELIKODVORSKAYA, GALINA A.