| 发明名称 |
A METHOD OF GENETICALLY MODIFYING VERY PRIMITIVE QUIESCENT HUMAN HEMATOPOIETIC STEM CELLS |
| 摘要 |
This invention relates to a method for transducing extremely primitive hematopoietic stem cells with high efficiency, using an adeno-associated vector. This vector stably transforms highly primitive CD34<+++>CD38<=> cells which reside in a quiescent state and retain to a larger extent the ability to repopulate the hematopoietic system.
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| 申请公布号 |
WO0034495(A2) |
申请公布日期 |
2000.06.15 |
| 申请号 |
WO1999US28539 |
申请日期 |
1999.12.03 |
| 申请人 |
CITY OF HOPE |
发明人 |
CHATTERJEE, SASWATI;WONG, KAMEHAMEHA, K., JR.;WONG, CHRISTIE, ANN |
| 分类号 |
A61P3/00;A61P31/00;C12N7/01;C12N15/864;(IPC1-7):C12N15/86;C12N5/10 |
主分类号 |
A61P3/00 |
| 代理机构 |
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