发明名称 ACTIVATION AND PROTECTION OF T-CELLS (CD4<+> AND CD8<+>) USING AN H2 RECEPTOR AGONIST AND OTHER T-CELL ACTIVATING AGENTS
摘要 The present invention relates to a method for facilitating activation of T-cells in a patient, comprising: identifying a patient in need of enhanced T-cell activity, administering an effective amount of a T-cell activating composition to the patient, and administering an effective amount of a compound that inhibits the production or release of intercellular reactive oxygen metabolites (ROM) to the patient. The present invention further relates to the use of H2-receptor agonists to augment the effectiveness of vaccines.
申请公布号 WO0010600(A3) 申请公布日期 2000.06.15
申请号 WO1999US19211 申请日期 1999.08.24
申请人 MAXIM PHARMACEUTICALS, INC. 发明人 HELLSTRAND, KRISTOFFER;HERMODSSON, SVANTE;GEHLSEN, KURT, R.
分类号 A61K31/13;A61K31/137;A61K31/138;A61K31/166;A61K31/17;A61K31/196;A61K31/198;A61K31/255;A61K31/352;A61K31/4045;A61K31/407;A61K31/4166;A61K31/4168;A61K31/4172;A61K31/475;A61K31/513;A61K31/519;A61K31/52;A61K31/522;A61K31/525;A61K31/5513;A61K31/662;A61K31/704;A61K31/7048;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61K31/7135;A61K33/24;A61K35/12;A61K38/00;A61K38/20;A61K38/21;A61K39/00;A61K39/04;A61K39/106;A61K39/145;A61K39/21;A61K39/265;A61K39/29;A61K39/39;A61K45/00;A61K45/06;A61P31/12;A61P35/00;A61P37/04;(IPC1-7):A61K39/00;A61K31/35;A61K39/02;A61K39/12 主分类号 A61K31/13
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