发明名称 USE OF IBANDRONATE FOR PROMOTING OSSEOINTEGRATION OF ENDOPROSTHESES
摘要 The invention relates to use of ibandronic acid (1-hydroxy-3-(N-methyl-N-pentyl)aminopropyl-1,1-diphosphonic acid) or physiologically compatible salts or esters thereof for improving the osseointegration of cement-free anchored endoprostheses. Ibandronate or salts thereof is applied for a short time immediately after insertion of an endoprosthesis, with the surprising result that secondary stability of the implant is obtained in only 5 weeks or less after the operation.
申请公布号 WO0033849(A1) 申请公布日期 2000.06.15
申请号 WO1999EP09252 申请日期 1999.11.29
申请人 ROCHE DIAGNOSTICS GMBH;BAUSS, FRIEDER;KURTH, ANDREAS, A. 发明人 BAUSS, FRIEDER;KURTH, ANDREAS, A.
分类号 A61K31/66;A61K31/663;A61P19/00;A61P19/02;(IPC1-7):A61K31/663 主分类号 A61K31/66
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