发明名称 |
Compositions and methods for generating red chemiluminescence |
摘要 |
Compounds which generate red chemiluminescence on reaction with a phosphatase enzyme are provided as well as intermediates useful for their preparation. The chemiluminescent compounds comprise a luciferin ring system and an exocyclic enol phosphate group where the position on the luciferin ring system adjacent to the double bond is disubstituted. The chemiluminescent compounds are useful alone or within compositions containing a cationic aromatic compound in methods for producing chemiluminescence. The chemiluminescent reactions can be applied in assays for phosphatase enzymes and in assays employing enzyme-labeled specific binding pairs. |
申请公布号 |
AU6177999(A) |
申请公布日期 |
2000.06.15 |
申请号 |
AU19990061779 |
申请日期 |
1999.11.30 |
申请人 |
LUMIGEN, INC. |
发明人 |
HASHEM AKHAVAN-TAFTI |
分类号 |
C07D277/66;C07F9/576;C07F9/64;C07F9/6541;C12Q1/42;G01N21/78 |
主分类号 |
C07D277/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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