摘要 |
<p>Agents capable of inhibiting the proliferation of cancer cells and cancers in the tissues therearound or unaffected tissues. Specifically, carcinostatic agents containing as the active ingredient mannan-binding proteins or genes thereof. The mannan-binding proteins include a protein having the amino acid sequence represented by SEQ ID NO:1 in the Sequence Listing and proteins having amino acid sequences derived therefrom by at least one of substitution, deletion, addition and insertion of one or more amino acids and having the activity as a mannan-binding protein. The above genes are exemplified by those encoding the amino acid sequences represented by SEQ ID NO:1 or 2 in the Sequence Listing, those encoding amino acid sequences derived therefrom by modification, and genes containing these genes.</p> |