发明名称 |
PCA3, PCA3 GENES, AND METHODS OF USE |
摘要 |
The present invention relates, in general, to a prostate-specific antigen, PCA3. In particular, the present invention relates to nucleic acid molecules coding for the PCA3 protein; purified PCA3 proteins and polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to PCA3 proteins and polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of nucleic acids encoding PCA3 proteins; a method of detecting nucleic acids encoding PCA3 proteins or polypeptides in a sample; kits containing nucleic acid probes or antibodies; bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with prostate cancer; therapeutic uses; and methods of preventing prostate cancer in an animal. |
申请公布号 |
EP1007650(A1) |
申请公布日期 |
2000.06.14 |
申请号 |
EP19980916696 |
申请日期 |
1998.04.09 |
申请人 |
STICHTING KATHOLIEKE UNIVERSITEIT, THE UNIVERSITYMEDICAL CENTRE NIJMEGEN |
发明人 |
BUSSEMAKERS, MARION, J., G.;ISAACS, WILLIAM BREWSTER |
分类号 |
A01K67/027;A61K31/711;A61K38/00;A61K39/395;A61K48/00;A61P13/08;A61P35/00;C07K14/47;C07K16/18;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/68;G01N33/577 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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