FRACTIONATED SUBSTANCE OF EXTRACT FROM MYCELIUM OF LENTINUS EDODES SING. AND USE THEREOF

摘要

PROBLEM TO BE SOLVED: To obtain an insoluble fraction having protecting effects on hepatic dysfunction without adverse effects, usable with administration of a drug causing the hepatic dysfunction and excellent in safety by treating an extract from a mycelium of Lentinus edodes Sing. with a solution containing ethanol. SOLUTION: This fractionated substance is obtained by treatment of an extract from a mycelium of Lentinus edodes Sing. with a solution containing ethanol. Furthermore, the insoluble fraction is preferably formulated with a pharmaceutically acceptable carrier as an optional ingredient to prepare a therapeutic and/or a prophylatic composition for hepatopathy. The protecting agent for the hepatopathy is for oral use and useful for foods and beverages. The daily dose of the ethanol-insoluble fraction is preferably within the range of 80-360 mg.