OSTEOGENESIS PROMOTION WITH USE OF VITAMIN D DERIVATIVES

摘要

An osteogenesis promotion with use of a vitamin D derivative of the formula: (see formula I) wherein R1, R2 and R3, which may be the same or different, each represents a hydrogen atom or a hydroxyl group; and R4 is a hydrogen atom or a lower alkyl group having 4 - 6 carbon atoms that may or may not be substituted by a hydroxyl group, are disclosed. A pharmaceutical composition comprising the above derivatives is useful as a therapeutic agent for osteoporosis.