| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject new inhibitor useful as a therapeutic agent or a preventive for diseases such as chronic glomerulus nephritis, arteriosclerosis, adult T-cell leukemia, etc., comprising a low molecular weight compound as an active ingredient by making the inhibitor include oleanolic acid or its salt as an active ingredient. SOLUTION: This inhibitor comprises oleanolic acid of the formula or its salt as an active ingredient. The active ingredient in an amount of 0.01-1,000 mg is generally administered daily twice or three times dividedly per adult. The compound of the formula is obtained by a method for extraction/separation from a plant such as olive leaf, Swertia japonica, Eugenia aromatica, etc., or a method for subjecting saponin existing in carrot, sugar beet, etc., to acid hydrolysis. The objective inhibitor can be used as an oral medicine such as tablet, granule, etc., or an external preparation such as ointment an injection.
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