| 发明名称 |
Substituted pyrazoles as p38 kinase inhibitors |
| 摘要 |
A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (IA), <CHEM> wherein R<1>, R<2>, R<3> and R<4> are as described in the specification. |
| 申请公布号 |
AU2145400(A) |
申请公布日期 |
2000.06.13 |
| 申请号 |
AU20000021454 |
申请日期 |
1999.11.17 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
ASHOK ANANTANARAYAN;MICHAEL CLARE;PAUL W. COLLINS;JOYCE Z. CRICH;RAJESH DEVRAJ;DANIEL L. FLYNN;LIFENG GENG;MATTHEW J GRANETO;CATHLEEN E. HANAU;GUNNAR J. HANSON;SUSAN J. HARTMANN;MICHAEL HEPPERLE;HE HUANG;ISH K. KHANNA;FRANCIS J KOSZYK;SHUYUAN LIAO;SUZANNE METZ;RICHARD A. PARTIS;THAO D. PERRY;SHASHIDHAR N RAO;SHAUN RAJ SELNESS;MICHAEL S. SOUTH;MICHAEL A STEALEY;JOHN, JEFFREY TALLY;MICHAEL L VAZQUEZ;RICHARD M. WEIER;XIANGDONG XU;YI YU |
| 分类号 |
A61K31/415;A61K31/44;A61K31/4439;A61K31/445;A61K31/454;A61K31/47;A61K31/496;A61K31/50;A61K31/505;A61K31/506;A61K31/52;A61K31/5377;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P19/00;A61P19/02;A61P19/06;A61P29/00;A61P29/02;A61P43/00;C07D401/04;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D453/02;C07D471/04;C07D473/00;C07D487/04 |
主分类号 |
A61K31/415 |
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