| 发明名称 |
PYRIDINE DERIVATIVES |
| 摘要 |
Pyridine derivatives of formula (see formula I) their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0, 1 and 2 and R,R1,R2 and R2 have specified meanings. The compounds exhibit activity as 5-HT1A agonists, antagonists or partial agonists and are useful for the treatment of CNS disorders eg anxiety, as antihypertensives and in treating anorexia.
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| 申请公布号 |
CA2014062(C) |
申请公布日期 |
2000.06.13 |
| 申请号 |
CA19902014062 |
申请日期 |
1990.04.06 |
| 申请人 |
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发明人 |
CLIFFE, IAN ANTHONY;WHITE, ALAN CHAPMAN;MANSELL, HOWARD LANGHAM;TODD, RICHARD SIMON |
| 分类号 |
A61K31/00;A61K31/435;A61K31/47;A61K31/4709;A61K31/473;A61P43/00;C07D215/38;C07D221/04;C07D401/12;C07D401/14;C07D405/12;C07D413/12;C07D417/12;C07D513/04;(IPC1-7):C07D215/38;C07D405/02;C07D401/10;C07D403/10;C07D413/10;C07D417/10;C07D221/16;A61K31/395 |
主分类号 |
A61K31/00 |
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