A PROCESS FOR THE PREPARATION OF N,N'-BIS[2, 3-DIHYDROXYPROPYL] -5-[ (HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE

摘要

A novel process for the preparation of N,N'-bis[2, 3-dihydroxypropyl] -5-[ (hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as Iomeprol, a novel non-ionic contrast agent which shows very good safety and contrast effectiveness.