A process is provided for expanding the population of endothelial cells obtained from peripheral blood which can be transformed with a vector comprising a DNA sequence encoding a preselected bioactive polypeptide. The resulting transgenic endothelial cells are useful to biocompatibilize implantable medical devices or can be used directly, as for gene therapy.
申请公布号
WO0032750(A1)
申请公布日期
2000.06.08
申请号
WO1999US28033
申请日期
1999.11.24
申请人
REGENTS OF THE UNIVERSITY OF MINNESOTA;EMORY UNIVERSITY;HEBBEL, ROBERT, P.;LIN, YI;LOLLAR, JOHN, S.