| 发明名称 |
3,4,5-TRISUBSTITUTED ARYL NITRONE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| 摘要 |
Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitron e compounds have formula (I); where R1-R4 are as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-relat ed conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.
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| 申请公布号 |
CA2353402(A1) |
申请公布日期 |
2000.06.08 |
| 申请号 |
CA19992353402 |
申请日期 |
1999.12.01 |
| 申请人 |
CENTAUR PHARMACEUTICALS, INC. |
发明人 |
CARNEY, JOHN M.;MAVANDADI, FARAH;DANIELZADEH, ALBERT;WATERBURY, L. DAVID;WILCOX, ALLAN L. |
| 分类号 |
A61P19/02;A61K;A61K31/135;A61K31/15;A61K31/235;A61K31/325;A61P19/00;A61P25/00;A61P29/00;A61P37/00;C07C;C07C291/02;C07C323/47;(IPC1-7):C07C291/02 |
主分类号 |
A61P19/02 |
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