发明名称 |
RECEPTOR THAT BINDS TRAIL |
摘要 |
A protein designated TRAIL receptor binds the protein known as TNF-Related Apoptosis-Inducing Ligand (TRAIL). The TRAIL receptor finds use in purifying TRAIL or inhibiting activities thereof. Isolated DNA sequences encoding TRAIL-R polypeptides are provided, along with expression vectors containing the DNA sequences, and host cells transformed with such recombinant expression vectors. Antibodies that are immunoreactive with TRAIL-R are also provided. |
申请公布号 |
EP1005488(A1) |
申请公布日期 |
2000.06.07 |
申请号 |
EP19980908474 |
申请日期 |
1998.02.11 |
申请人 |
IMMUNEX CORPORATION |
发明人 |
RAUCH, CHARLES;WALCZAK, HENNING, DR. |
分类号 |
C12N15/09;A61K38/00;A61P43/00;C07K14/705;C07K14/715;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/08;(IPC1-7):C07K14/435;C12N15/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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