| 发明名称 |
Spiro-piperidine derivatives and their use as therapeutic agents |
| 摘要 |
PCT No. PCT/GB97/01630 Sec. 371 Date Dec. 16, 1998 Sec. 102(e) Date Dec. 16, 1998 PCT Filed Jun. 17, 1997 PCT Pub. No. WO97/49710 PCT Pub. Date Dec. 31, 1997The present invention relates to certain spiro-piperdine derivatives which are tachykinnin antagonists and are useful, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
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| 申请公布号 |
US6071927(A) |
申请公布日期 |
2000.06.06 |
| 申请号 |
US19980202493 |
申请日期 |
1998.12.16 |
| 申请人 |
MERCK SHARP & DOHME LTD. |
发明人 |
BAKER, RAYMOND;CURTIS, NEIL ROY;ELLIOTT, JASON MATTHEW;HARRISON, TIMOTHY;HOLLINGWORTH, GREGORY JOHN;JACKSON, PHILIP STEPHEN;KULAGOWSKI, JANUSZ JOZEF;SEWARD, EILEEN MARY;SWAIN, CHRISTOPHER JOHN;WILLIAMS, BRIAN JOHN |
| 分类号 |
A61K31/00;A61K31/395;A61K31/435;A61K31/438;A61K31/445;A61K31/451;A61K31/5375;A61K31/5377;A61K31/675;A61P1/00;A61P1/08;A61P25/04;A61P25/06;A61P29/00;A61P43/00;C07D211/56;C07D491/10;C07D491/107;(IPC1-7):A61K31/435;C07D211/06 |
主分类号 |
A61K31/00 |
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