| 发明名称 |
Method for treating tumors using 2-aryl-naphthyridin-4-ones |
| 摘要 |
The present invention provides compounds of Formula I: wherein A and R1-R8 are defined herein. The compounds of Formula I inhibit the polymerization of tubulin and possess antimitotic activity. The compounds of Formula I may be useful for the treatment of psoriasis, gout, papiloma, warts, and a variety of tumors.
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| 申请公布号 |
US6071930(A) |
申请公布日期 |
2000.06.06 |
| 申请号 |
US19990363101 |
申请日期 |
1999.07.29 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
LEE, KUO-HSIUNG;CHEN, KE;KUO, SHENG-CHU |
| 分类号 |
A61K31/4375;A61P17/06;A61P19/06;A61P35/00;A61P43/00;C07D213/74;C07D471/04;(IPC1-7):A61K31/437 |
主分类号 |
A61K31/4375 |
| 代理机构 |
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