发明名称 Lipid vesicles formed with alkylammonium fatty acid salts
摘要 The present invention provides for liposomes formed with alkylammonium fatty acid salts, and methods for manufacturing same. The liposomes of the invention may deliver entrapped load material or materials at the occurrence of a preset triggering condition. Preferred liposomes of the invention are cationic liposomes. The preferred liposomes of the invention are formed with alkylammonium fatty acid salts, e.g., trialkylammonium fatty acid salts of long chain amides. The liposomes of the invention are used to encapsulate both hydrophobic and hydrophilic load materials. The liposomes formed accordingly are capable of delivering their loads upon the occurrence of a trigger or control condition.
申请公布号 US6071535(A) 申请公布日期 2000.06.06
申请号 US19990255160 申请日期 1999.02.22
申请人 COLLABORATIVE LABORATORIES, INC. 发明人 HAYWARD, JAMES A.;WATKINS, DAVID C.;AUST, DUNCAN T.
分类号 A61K9/127;(IPC1-7):A61K9/127;A61K9/133;A61K7/00 主分类号 A61K9/127
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