| 摘要 |
PCT No. PCT/EP97/06855 Sec. 371 Date Jun. 16, 1999 Sec. 102(e) Date Jun. 16, 1999 PCT Filed Dec. 9, 1997 PCT Pub. No. WO98/28250 PCT Pub. Date Jul. 2, 1998The present invention relates to a process for the preparation of carbonyl compounds of the formula in which R1 denotes a hydrogen atom or an alkyl radical containing from 1 to 3 carbon atoms, R2 denotes a hydrogen atom or a radical of the formula in which R3 denotes a hydrogen atom or, together with R4, an oxygen atom, R4 denotes the radical OR6 or, together with R3, an oxygen atom, R5 denotes a hydrogen atom or an alkyl radical containing from 1 to 8 carbon atoms or a cyclohexyl or cyclopentyl radical, and R6 denotes an alkyl radical containing from 1 to 4 carbon atoms, a cyclohexyl or cyclopentyl radical or a radical of the formula -CH2-CHO or -CH2-CH2-O-CH2-CHO, by gas-phase oxidation of methanol or alcohols of the formula in which R1 and R5 have the meanings specified above and R7 denotes a hydrogen atom or a radical OR8, and R8 denotes a hydrogen atom, an alkyl radical containing from 1 to 4 carbon atoms, a cyclohexyl or cyclopentyl radical or a radical of the formula -CH2-CH2-OH or -CH2-CH2-O-CH2-CH2-OH, using an oxygen-containing gas in the presence of a (copper and/or silver)-containing catalyst and a phosphorus compound which is volatile under the conditions of the reaction and is present in an amount such that the weight of phosphorus (calculated as P), based on the weight of alcohol used, is not more than 20 ppm, wherein the amount of phosphorus used is divided into at least two portions, of which a) the first portion is added together with the mixture of gaseous starting materials before this reaches the catalyst bed and b) at least one further portion is added within the catalyst bed.
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