Nucleic acid transporters and medicinal compositions for gene therapy

摘要

A novel nucleic acid carrier and a pharmaceutical composition for gene therapy are disclosed. The nucleic acid carrier of this invention is characterized by containing a polypeptide comprising diaminobutyric acid with a suitable number of residues and/or a pharmaceutically acceptable salt thereof. The nucleic acid carrier of this invention can form a complex with a variety of therapeutic genes that is safe and has extremely low immunogenicity (the pharmaceutical composition of this invention); and it can allow the therapeutic gene to be introduced into cells efficiently and safely whereby high expression of the gene in the cells can be realized.