摘要 |
<p>Compounds represented by general formula (I), salts thereof or prodrugs of the same which exhibit an excellent effect of inhibiting β-amyloid protein production/secretion, wherein Ar represents an aromatic group; X and Y represent each a divalent group selected from among -O-, -S-, -CO-, -SO-, -SO2-, -NR8-, -CONR8-, -SO¿2NR?8- and -COO- (wherein R8 represents H, hydrocarbyl or acyl), or divalent aliphatic C¿1-6? hydrocarbyl optionally containing one or two of these divalent groups; R?1 and R2¿ represent each H or C¿1-6? alkyl, or R?1 and R2¿ may form together with the nitrogen atom adjacent thereto a nitrogen-containing heterocycle; and the ring A represents a monocyclic aromatic ring.</p> |