TUMOR ANTIGEN-SPECIFIC ANTIBODY-GP39 CHIMERIC PROTEIN CONSTRUCTS

摘要

This invention relates generally to the production of antigen-binding chimeric proteins also comprising an immunoeffector binding domain. More specifically, the invention relates to chimeric proteins comprising a tumor antigen-specific antibody or antibody fragment fused to the CD40 ligand, gp39. Compositions comprising, genetic constructions for, methods of use, and methods for producing the chimeric proteins are also disclosed.