beta -AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS

摘要

Compounds represented by general formula (I), salts thereof or prodrugs of the same which exhibit an excellent effect of inhibiting beta -amyloid protein production/secretion, wherein Ar represents an aromatic group; X and Y represent each a divalent group selected from among -O-, -S-, -CO-, -SO-, -SO2-, -NR<8>-, -CONR<8>-, -SO2NR<8>- and -COO- (wherein R<8> represents H, hydrocarbyl or acyl), or divalent aliphatic C1-6 hydrocarbyl optionally containing one or two of these divalent groups; R<1> and R<2> represent each H or C1-6 alkyl, or R<1> and R<2> may form together with the nitrogen atom adjacent thereto a nitrogen-containing heterocycle; and the ring A represents a monocyclic aromatic ring.